PDB 5t8f

PDB Information

PDB5T8F
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design of Tricyclic NF-kappa B Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K).
Castanedo, G.M., Blaquiere, N., Beresini, M., Bravo, B., Brightbill, H., Chen, J., Cui, H.F., Eigenbrot, C., Everett, C., Feng, J., Godemann, R., Gogol, E., Hymowitz, S., Johnson, A., Kayagaki, N., Kohli, P.B., Knuppel, K., Kraemer, J., Kruger, S., Loke, P., McEwan, P., Montalbetti, C., Roberts, D.A., Smith, M., Steinbacher, S., Sujatha-Bhaskar, S., Takahashi, R., Wang, X., Wu, L.C., Zhang, Y., Staben, S.T.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-09-07
Resolution2.910
CATH Insert Date07 May, 2017

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Holding pen
B 08 May, 2017 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P23727 P85A_BOVIN Bos taurus Phosphatidylinositol 3-kinase regulatory subunit alpha
O00329 PK3CD_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform