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PDB Information
| PDB | 5SXF |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Homo sapiens |
| Primary Citation |
Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design.
Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B.
Bioorg. Med. Chem.
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2016-08-09 |
| Resolution | 3.460 |
| CATH Insert Date | 07 May, 2017 |
PDB Chains (2)
CATH Domains (0)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
UniProtKB Entries (2)
| Accession |
Gene ID |
Taxon |
Description |
| P42336 |
PK3CA_HUMAN |
Homo sapiens |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform |
| P27986 |
P85A_HUMAN |
Homo sapiens |
Phosphatidylinositol 3-kinase regulatory subunit alpha |