PDB Information

PDB5SWO
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Identification of allosteric binding sites for PI3K alpha oncogenic mutant specific inhibitor design.
Miller, M.S., Maheshwari, S., McRobb, F.M., Kinzler, K.W., Amzel, L.M., Vogelstein, B., Gabelli, S.B.
Bioorg. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-08-08
Resolution3.500
CATH Insert Date07 May, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Holding pen
B 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5swoB01 14 Nov, 2017 Holding pen
5swoB02 14 Nov, 2017 1.10.287.1490 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27986 P85A_HUMAN Homo sapiens Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336 PK3CA_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform