PDB 5svf

PDB Information

PDB5SVF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity.
Xie, X., Baird, D., Bowen, K., Capka, V., Chen, J., Chenail, G., Cho, Y., Dooley, J., Farsidjani, A., Fortin, P., Kohls, D., Kulathila, R., Lin, F., McKay, D., Rodrigues, L., Sage, D., Toure, B.B., van der Plas, S., Wright, K., Xu, M., Yin, H., Levell, J., Pagliarini, R.A.
Structure
HeaderOxidoreductase
Released2016-08-05
Resolution2.340
CATH Insert Date07 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
B 08 May, 2017 Chopped
C 08 May, 2017 Chopped
D 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5svfA00 20 May, 2017 3.40.718.10 Assigned
5svfB00 20 May, 2017 3.40.718.10 Assigned
5svfC00 20 May, 2017 3.40.718.10 Assigned
5svfD00 20 May, 2017 3.40.718.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic