PDB 5qcn

PDB Information

PDB5QCN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).
Pinto, D.J.P., Orwat, M.J., Smith, L.M., Quan, M.L., Lam, P.Y.S., Rossi, K.A., Apedo, A., Bozarth, J.M., Wu, Y., Zheng, J.J., Xin, B., Toussaint, N., Stetsko, P., Gudmundsson, O., Maxwell, B., Crain, E.J., Wong, P.C., Lou, Z., Harper, T.W., Chacko, S.A., Myers, J.E., Sheriff, S., Zhang, H., Hou, X., Mathur, A., Seiffert, D.A., Wexler, R.R., Luettgen, J.M., Ewing, W.R.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-08-10
Resolution2.300
CATH Insert Date17 Dec, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5qcnA01 22 Dec, 2017 Holding pen
5qcnA02 22 Dec, 2017 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI