PDB 5qck

PDB Information

PDB5QCK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a Parenteral Small Molecule Coagulation Factor XIa Inhibitor Clinical Candidate (BMS-962212).
Pinto, D.J.P., Orwat, M.J., Smith, L.M., Quan, M.L., Lam, P.Y.S., Rossi, K.A., Apedo, A., Bozarth, J.M., Wu, Y., Zheng, J.J., Xin, B., Toussaint, N., Stetsko, P., Gudmundsson, O., Maxwell, B., Crain, E.J., Wong, P.C., Lou, Z., Harper, T.W., Chacko, S.A., Myers, J.E., Sheriff, S., Zhang, H., Hou, X., Mathur, A., Seiffert, D.A., Wexler, R.R., Luettgen, J.M., Ewing, W.R.
J. Med. Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2017-08-10
Resolution2.640
CATH Insert Date17 Dec, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Dec, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5qckA01 22 Dec, 2017 Holding pen
5qckA02 22 Dec, 2017 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI