PDB Information

PDB5OCO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.
Quevedo, C.E., Cruz-Migoni, A., Bery, N., Miller, A., Tanaka, T., Petch, D., Bataille, C.J.R., Lee, L.Y.W., Fallon, P.S., Tulmin, H., Ehebauer, M.T., Fernandez-Fuentes, N., Russell, A.J., Carr, S.B., Phillips, S.E.V., Rabbitts, T.H.
Nat Commun
HeaderHydrolase
Released2017-07-03
Resolution1.660
CATH Insert Date26 Aug, 2018

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 26 Aug, 2018 Chopped
B 26 Aug, 2018 Chopped
C 26 Aug, 2018 Chopped
D 26 Aug, 2018 Chopped
E 26 Aug, 2018 Chopped
F 26 Aug, 2018 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5ocoA00 27 Aug, 2018 3.40.50.300 Assigned
5ocoB00 27 Aug, 2018 3.40.50.300 Assigned
5ocoC00 27 Aug, 2018 3.40.50.300 Assigned
5ocoD00 27 Aug, 2018 3.40.50.300 Assigned
5ocoE00 27 Aug, 2018 3.40.50.300 Assigned
5ocoF00 27 Aug, 2018 3.40.50.300 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas
P01116 RASK_HUMAN Homo sapiens GTPase KRas