PDB Information

PDB5O76
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants.
Gabrielsen, M., Buetow, L., Nakasone, M.A., Ahmed, S.F., Sibbet, G.J., Smith, B.O., Zhang, W., Sidhu, S.S., Huang, D.T.
Mol. Cell
HeaderLigase
Released2017-06-08
Resolution2.470
CATH Insert Date14 Nov, 2017

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Rejected
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Rejected
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5o76A01 09 May, 2018 1.20.930.20 Assigned
5o76A02 09 May, 2018 Holding pen
5o76A03 09 May, 2018 3.30.505.10 Assigned
5o76A04 09 May, 2018 3.30.40.10 Assigned
5o76C01 09 May, 2018 1.20.930.20 Assigned
5o76C02 09 May, 2018 Holding pen
5o76C03 09 May, 2018 3.30.505.10 Assigned
5o76C04 09 May, 2018 3.30.40.10 Assigned
5o76E00 16 Dec, 2017 Holding pen
5o76F00 16 Dec, 2017 Holding pen

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P43403 ZAP70_HUMAN Homo sapiens Tyrosine-protein kinase ZAP-70
P22681 CBL_HUMAN Homo sapiens E3 ubiquitin-protein ligase CBL
P22681 CBL_HUMAN Homo sapiens E3 ubiquitin-protein ligase CBL
P43403 ZAP70_HUMAN Homo sapiens Tyrosine-protein kinase ZAP-70