PDB 5o3b

PDB Links
Overview

PDB Information

PDB	5O3B
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21
Gene Source	Homo sapiens
Primary Citation	Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Runcie, A.C., Zengerle, M., Chan, K.H., Testa, A., van Beurden, L., Baud, M.G.J., Epemolu, O., Ellis, L.C.J., Read, K.D., Coulthard, V., Brien, A., Ciulli, A. Chem Sci
Header	Transcription
Released	2017-05-23
Resolution	1.950
CATH Insert Date	03 Jun, 2018

PDB Images (9)

Image of CATH 5o3b

5o3b

PDB 5o3b

Image of CATH 5o3bA

5o3bA

PDB Chain 5o3bA

Image of CATH 5o3bB

5o3bB

PDB Chain 5o3bB

Image of CATH 5o3bC

5o3bC

PDB Chain 5o3bC

Image of CATH 5o3bD

5o3bD

PDB Chain 5o3bD

Image of CATH 5o3bA00

5o3bA00

CATH Domain 5o3bA00

Image of CATH 5o3bB00

5o3bB00

CATH Domain 5o3bB00

Image of CATH 5o3bC00

5o3bC00

CATH Domain 5o3bC00

Image of CATH 5o3bD00

5o3bD00

CATH Domain 5o3bD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	03 Jun, 2018	Chopped
B	03 Jun, 2018	Chopped
C	03 Jun, 2018	Chopped
D	03 Jun, 2018	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5o3bA00	27 Jun, 2018	1.20.920.10	Assigned
5o3bB00	27 Jun, 2018	1.20.920.10	Assigned
5o3bC00	27 Jun, 2018	1.20.920.10	Assigned
5o3bD00	27 Jun, 2018	1.20.920.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2