PDB Information

PDB5O1D
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines.
Baud, M.G.J., Bauer, M.R., Verduci, L., Dingler, F.A., Patel, K.J., Horil Roy, D., Joerger, A.C., Fersht, A.R.
Eur J Med Chem
HeaderDna Binding Protein
Released2017-05-18
Resolution1.360
CATH Insert Date03 Jun, 2018

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped
B 03 Jun, 2018 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5o1dA00 27 Jun, 2018 2.60.40.720 Assigned
5o1dB00 27 Jun, 2018 2.60.40.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53
P04637 P53_HUMAN Homo sapiens Cellular tumor antigen p53