PDB 5nhy

PDB Information

PDB5NHY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target.
Ellermann, M., Eheim, A., Rahm, F., Viklund, J., Guenther, J., Andersson, M., Ericsson, U., Forsblom, R., Ginman, T., Lindstrom, J., Silvander, C., Tresaugues, L., Giese, A., Bunse, S., Neuhaus, R., Weiske, J., Quanz, M., Glasauer, A., Nowak-Reppel, K., Bader, B., Irlbacher, H., Meyer, H., Queisser, N., Bauser, M., Haegebarth, A., Gorjanacz, M.
ACS Chem. Biol.
HeaderHydrolase
Released2017-03-22
Resolution1.720
CATH Insert Date14 Nov, 2017

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5nhyA00 10 Dec, 2017 3.90.79.10 Assigned
5nhyB00 10 Dec, 2017 3.90.79.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P36639 8ODP_HUMAN Homo sapiens 7,8-dihydro-8-oxoguanine triphosphatase
P36639 8ODP_HUMAN Homo sapiens 7,8-dihydro-8-oxoguanine triphosphatase