PDB Information

PDB5NGE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Molecular basis of USP7 inhibition by selective small-molecule inhibitors.
Turnbull, A.P., Ioannidis, S., Krajewski, W.W., Pinto-Fernandez, A., Heride, C., Martin, A.C.L., Tonkin, L.M., Townsend, E.C., Buker, S.M., Lancia, D.R., Caravella, J.A., Toms, A.V., Charlton, T.M., Lahdenranta, J., Wilker, E., Follows, B.C., Evans, N.J., Stead, L., Alli, C., Zarayskiy, V.V., Talbot, A.C., Buckmelter, A.J., Wang, M., McKinnon, C.L., Saab, F., McGouran, J.F., Century, H., Gersch, M., Pittman, M.S., Marshall, C.G., Raynham, T.M., Simcox, M., Stewart, L.M.D., McLoughlin, S.B., Escobedo, J.A., Bair, K.W., Dinsmore, C.J., Hammonds, T.R., Kim, S., Urbe, S., Clague, M.J., Kessler, B.M., Komander, D.
Nature
HeaderHydrolase
Released2017-03-17
Resolution2.350
CATH Insert Date14 Nov, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5ngeA01 05 May, 2018 Holding pen
5ngeA02 05 May, 2018 2.20.210.10 Assigned
5ngeA03 05 May, 2018 Holding pen
5ngeB00 04 May, 2018 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q93009 UBP7_HUMAN Homo sapiens Ubiquitin carboxyl-terminal hydrolase 7
Q93009 UBP7_HUMAN Homo sapiens Ubiquitin carboxyl-terminal hydrolase 7