PDB 5n1x

PDB Information

PDB5N1X
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris
Gene SourceHomo sapiens
Primary Citation
Discovery of Pyrazolo[1,5-a]pyrimidine B-Cell Lymphoma 6 (BCL6) Binders and Optimization to High Affinity Macrocyclic Inhibitors.
McCoull, W., Abrams, R.D., Anderson, E., Blades, K., Barton, P., Box, M., Burgess, J., Byth, K., Cao, Q., Chuaqui, C., Carbajo, R.J., Cheung, T., Code, E., Ferguson, A.D., Fillery, S., Fuller, N.O., Gangl, E., Gao, N., Grist, M., Hargreaves, D., Howard, M.R., Hu, J., Kemmitt, P.D., Nelson, J.E., O'Connell, N., Prince, D.B., Raubo, P., Rawlins, P.B., Robb, G.R., Shi, J., Waring, M.J., Whittaker, D., Wylot, M., Zhu, X.
J. Med. Chem.
HeaderTransferase
Released2017-02-06
Resolution1.720
CATH Insert Date21 May, 2017

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 22 May, 2017 Chopped
B 22 May, 2017 Chopped
C 22 May, 2017 Chopped
D 22 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5n1xA00 06 Nov, 2017 3.30.710.10 Assigned
5n1xB00 06 Nov, 2017 3.30.710.10 Assigned
5n1xC00 06 Nov, 2017 3.30.710.10 Assigned
5n1xD00 06 Nov, 2017 3.30.710.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P41182 BCL6_HUMAN Homo sapiens B-cell lymphoma 6 protein
P41182 BCL6_HUMAN Homo sapiens B-cell lymphoma 6 protein
P41182 BCL6_HUMAN Homo sapiens B-cell lymphoma 6 protein
P41182 BCL6_HUMAN Homo sapiens B-cell lymphoma 6 protein