PDB Information

PDB5MXQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourcePseudomonas aeruginosa
Primary Citation
SAR Studies Leading to the Identification of a Novel Series of Metallo-beta-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.
Leiris, S., Coelho, A., Castandet, J., Bayet, M., Lozano, C., Bougnon, J., Bousquet, J., Everett, M., Lemonnier, M., Sprynski, N., Zalacain, M., Pallin, T.D., Cramp, M.C., Jennings, N., Raphy, G., Jones, M.W., Pattipati, R., Shankar, B., Sivasubrahmanyam, R., Soodhagani, A.K., Juventhala, R.R., Pottabathini, N., Pothukanuri, S., Benvenuti, M., Pozzi, C., Mangani, S., De Luca, F., Cerboni, G., Docquier, J.D., Davies, D.T.
Acs Infect Dis.
HeaderHydrolase
Released2017-01-24
Resolution2.000
CATH Insert Date03 Jun, 2018

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 03 Jun, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5mxqA00 27 Jun, 2018 3.60.15.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9K2N0 Q9K2N0_PSEAI Pseudomonas aeruginosa Beta-lactamase class B VIM-2