PDB 5mw4

PDB Links
Overview

PDB Information

PDB	5MW4
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach. Mobitz, H., Machauer, R., Holzer, P., Vaupel, A., Stauffer, F., Ragot, C., Caravatti, G., Scheufler, C., Fernandez, C., Hommel, U., Tiedt, R., Beyer, K.S., Chen, C., Zhu, H., Gaul, C. ACS Med Chem Lett
Header	Transferase
Released	2017-01-18
Resolution	2.190
CATH Insert Date	07 May, 2017

PDB Images (7)

Image of CATH 5mw4

5mw4

PDB 5mw4

Image of CATH 5mw4A

5mw4A

PDB Chain 5mw4A

Image of CATH 5mw4B

5mw4B

PDB Chain 5mw4B

Image of CATH 5mw4A01

5mw4A01

CATH Domain 5mw4A01

Image of CATH 5mw4A02

5mw4A02

CATH Domain 5mw4A02

Image of CATH 5mw4B01

5mw4B01

CATH Domain 5mw4B01

Image of CATH 5mw4B02

5mw4B02

CATH Domain 5mw4B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5mw4A01	17 May, 2017	1.10.260.60	Assigned
5mw4A02	17 May, 2017	3.40.50.150	Assigned
5mw4B01	17 May, 2017	1.10.260.60	Assigned
5mw4B02	17 May, 2017	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific