PDB 5mvs

PDB Links
Overview

PDB Information

PDB	5MVS
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Potent, Selective, and Structurally Novel Dot1L Inhibitors by a Fragment Linking Approach. Mobitz, H., Machauer, R., Holzer, P., Vaupel, A., Stauffer, F., Ragot, C., Caravatti, G., Scheufler, C., Fernandez, C., Hommel, U., Tiedt, R., Beyer, K.S., Chen, C., Zhu, H., Gaul, C. ACS Med Chem Lett
Header	Transferase
Released	2017-01-17
Resolution	2.180
CATH Insert Date	07 May, 2017

PDB Images (7)

Image of CATH 5mvs

5mvs

PDB 5mvs

Image of CATH 5mvsA

5mvsA

PDB Chain 5mvsA

Image of CATH 5mvsB

5mvsB

PDB Chain 5mvsB

Image of CATH 5mvsA01

5mvsA01

CATH Domain 5mvsA01

Image of CATH 5mvsA02

5mvsA02

CATH Domain 5mvsA02

Image of CATH 5mvsB01

5mvsB01

CATH Domain 5mvsB01

Image of CATH 5mvsB02

5mvsB02

CATH Domain 5mvsB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 May, 2017	Chopped
B	08 May, 2017	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5mvsA01	17 May, 2017	1.10.260.60	Assigned
5mvsA02	17 May, 2017	3.40.50.150	Assigned
5mvsB01	17 May, 2017	1.10.260.60	Assigned
5mvsB02	17 May, 2017	3.40.50.150	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3	DOT1L_HUMAN	Homo sapiens	Histone-lysine N-methyltransferase, H3 lysine-79 specific