PDB Information

PDB5MQF
MethodELECTRON MICROSCOPY
Host Organism
Gene Source
Primary Citation
Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Bertram, K., Agafonov, D.E., Liu, W.T., Dybkov, O., Will, C.L., Hartmuth, K., Urlaub, H., Kastner, B., Stark, H., Lu Hrmann, R.
Nature
HeaderSplicing
Released2016-12-20
Resolution5.900
CATH Insert Date07 May, 2017

PDB Images (47)

PDB Prints

PDB Chains (46)

Chain ID Date inserted into CATH CATH Status
2 08 May, 2017 Rejected
5 08 May, 2017 Rejected
6 08 May, 2017 Rejected
a 08 May, 2017 Rejected
A 08 May, 2017 Rejected
b 08 May, 2017 Rejected
B 08 May, 2017 Rejected
c 08 May, 2017 Rejected
C 08 May, 2017 Rejected
d 08 May, 2017 Rejected
D 08 May, 2017 Rejected
e 08 May, 2017 Rejected
E 08 May, 2017 Rejected
f 08 May, 2017 Rejected
F 08 May, 2017 Rejected
g 08 May, 2017 Rejected
G 08 May, 2017 Rejected
h 08 May, 2017 Rejected
H 08 May, 2017 Rejected
i 08 May, 2017 Rejected
I 08 May, 2017 Rejected
j 08 May, 2017 Rejected
J 08 May, 2017 Rejected
k 08 May, 2017 Rejected
K 08 May, 2017 Rejected
l 08 May, 2017 Rejected
L 08 May, 2017 Rejected
m 08 May, 2017 Rejected
M 08 May, 2017 Rejected
n 08 May, 2017 Rejected
N 08 May, 2017 Rejected
o 08 May, 2017 Rejected
O 08 May, 2017 Rejected
p 08 May, 2017 Rejected
P 08 May, 2017 Rejected
q 08 May, 2017 Rejected
Q 08 May, 2017 Rejected
R 08 May, 2017 Rejected
S 08 May, 2017 Rejected
T 08 May, 2017 Rejected
U 08 May, 2017 Rejected
V 08 May, 2017 Rejected
W 08 May, 2017 Rejected
X 08 May, 2017 Rejected
Y 08 May, 2017 Rejected
Z 08 May, 2017 Rejected

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (37)

Accession Gene ID Taxon Description
Q99459 CDC5L_HUMAN Homo sapiens Cell division cycle 5-like protein
Q6P2Q9 PRP8_HUMAN Homo sapiens Pre-mRNA-processing-splicing factor 8
O60508 PRP17_HUMAN Homo sapiens Pre-mRNA-processing factor 17
Q9NW64 RBM22_HUMAN Homo sapiens Pre-mRNA-splicing factor RBM22
Q14562 DHX8_HUMAN Homo sapiens ATP-dependent RNA helicase DHX8
P08579 RU2B_HUMAN Homo sapiens U2 small nuclear ribonucleoprotein B''
P62316 SMD2_HUMAN Homo sapiens Small nuclear ribonucleoprotein Sm D2
P62316 SMD2_HUMAN Homo sapiens Small nuclear ribonucleoprotein Sm D2
P09661 RU2A_HUMAN Homo sapiens U2 small nuclear ribonucleoprotein A'
P62304 RUXE_HUMAN Homo sapiens Small nuclear ribonucleoprotein E
P62308 RUXG_HUMAN Homo sapiens Small nuclear ribonucleoprotein G
O43660 PLRG1_HUMAN Homo sapiens Pleiotropic regulator 1
P41223 BUD31_HUMAN Homo sapiens Protein BUD31 homolog
P62308 RUXG_HUMAN Homo sapiens Small nuclear ribonucleoprotein G
O75934 SPF27_HUMAN Homo sapiens Pre-mRNA-splicing factor SPF27
P62314 SMD1_HUMAN Homo sapiens Small nuclear ribonucleoprotein Sm D1
Q9BZJ0 CRNL1_HUMAN Homo sapiens Crooked neck-like protein 1
Q9UMS4 PRP19_HUMAN Homo sapiens Pre-mRNA-processing factor 19
Q9UNP9 PPIE_HUMAN Homo sapiens Peptidyl-prolyl cis-trans isomerase E
Q9Y3C6 PPIL1_HUMAN Homo sapiens Peptidyl-prolyl cis-trans isomerase-like 1
P62306 RUXF_HUMAN Homo sapiens Small nuclear ribonucleoprotein F
Q96DI7 SNR40_HUMAN Homo sapiens U5 small nuclear ribonucleoprotein 40 kDa protein
Q15029 U5S1_HUMAN Homo sapiens 116 kDa U5 small nuclear ribonucleoprotein component
P62314 SMD1_HUMAN Homo sapiens Small nuclear ribonucleoprotein Sm D1
Q9HCG8 CWC22_HUMAN Homo sapiens Pre-mRNA-splicing factor CWC22 homolog
P62304 RUXE_HUMAN Homo sapiens Small nuclear ribonucleoprotein E
P62306 RUXF_HUMAN Homo sapiens Small nuclear ribonucleoprotein F
Q9UMS4 PRP19_HUMAN Homo sapiens Pre-mRNA-processing factor 19
Q9UMS4 PRP19_HUMAN Homo sapiens Pre-mRNA-processing factor 19
P62318 SMD3_HUMAN Homo sapiens Small nuclear ribonucleoprotein Sm D3
P62318 SMD3_HUMAN Homo sapiens Small nuclear ribonucleoprotein Sm D3
P14678 RSMB_HUMAN Homo sapiens Small nuclear ribonucleoprotein-associated proteins B and B'
P14678 RSMB_HUMAN Homo sapiens Small nuclear ribonucleoprotein-associated proteins B and B'
P38919 IF4A3_HUMAN Homo sapiens Eukaryotic initiation factor 4A-III
Q9HCS7 SYF1_HUMAN Homo sapiens Pre-mRNA-splicing factor SYF1
Q9UMS4 PRP19_HUMAN Homo sapiens Pre-mRNA-processing factor 19
O60306 AQR_HUMAN Homo sapiens Intron-binding protein aquarius