PDB Information

PDB5MLE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Zheng, Y., Sethi, R., Mangala, L.S., Taylor, C., Goldsmith, J., Wang, M., Masuda, K., Karaminejadranjbar, M., Mannion, D., Miranda, F., Herrero-Gonzalez, S., Hellner, K., Chen, F., Alsaadi, A., Albukhari, A., Fotso, D.C., Yau, C., Jiang, D., Pradeep, S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Knapp, S., Gray, N.S., Campo, L., Myers, K.A., Dhar, S., Ferguson, D., Bast, R.C., Sood, A.K., von Delft, F., Ahmed, A.A.
Nat Commun
HeaderHydrolase
Released2016-12-06
Resolution2.480
CATH Insert Date07 May, 2017

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped
C 08 May, 2017 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5mleA01 16 May, 2017 Check for nw result
5mleA02 16 May, 2017 Check for nw result
5mleC01 16 May, 2017 Check for nw result
5mleC02 16 May, 2017 Check for nw result

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q16555 DPYL2_HUMAN Homo sapiens Dihydropyrimidinase-related protein 2
Q16555 DPYL2_HUMAN Homo sapiens Dihydropyrimidinase-related protein 2