PDB 5mf4

PDB Information

PDB5MF4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.
Trigili, C., Barasoain, I., Sanchez-Murcia, P.A., Bargsten, K., Redondo-Horcajo, M., Nogales, A., Gardner, N.M., Meyer, A., Naylor, G.J., Gomez-Rubio, E., Gago, F., Steinmetz, M.O., Paterson, I., Prota, A.E., Diaz, J.F.
ACS Omega
HeaderCell Cycle
Released2016-11-17
Resolution2.300
CATH Insert Date14 Nov, 2017

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped
B 14 Nov, 2017 Chopped
C 14 Nov, 2017 Chopped
D 14 Nov, 2017 Chopped
E 14 Nov, 2017 Chopped
F 14 Nov, 2017 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
5mf4A01 10 Dec, 2017 3.40.50.1440 Assigned
5mf4A02 10 Dec, 2017 3.30.1330.20 Assigned
5mf4A03 10 Dec, 2017 1.10.287.600 Assigned
5mf4B01 10 Dec, 2017 3.40.50.1440 Assigned
5mf4B02 10 Dec, 2017 3.30.1330.20 Assigned
5mf4B03 10 Dec, 2017 1.10.287.600 Assigned
5mf4C01 10 Dec, 2017 3.40.50.1440 Assigned
5mf4C02 10 Dec, 2017 3.30.1330.20 Assigned
5mf4C03 10 Dec, 2017 1.10.287.600 Assigned
5mf4D01 10 Dec, 2017 3.40.50.1440 Assigned
5mf4D02 10 Dec, 2017 3.30.1330.20 Assigned
5mf4D03 10 Dec, 2017 1.10.287.600 Assigned
5mf4E01 10 Dec, 2017 6.10.280.30 Assigned
5mf4F01 10 Dec, 2017 3.40.50.11480 Assigned
5mf4F02 10 Dec, 2017 3.30.470.20 Assigned
5mf4F03 10 Dec, 2017 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain