PDB 5mar

PDB Information

PDB5MAR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Development of 1,2,4-Oxadiazoles as Potent and Selective Inhibitors of the Human Deacetylase Sirtuin 2: Structure-Activity Relationship, X-ray Crystal Structure, and Anticancer Activity.
Moniot, S., Forgione, M., Lucidi, A., Hailu, G.S., Nebbioso, A., Carafa, V., Baratta, F., Altucci, L., Giacche, N., Passeri, D., Pellicciari, R., Mai, A., Steegborn, C., Rotili, D.
J. Med. Chem.
HeaderHydrolase
Released2016-11-04
Resolution1.890
CATH Insert Date07 May, 2017

PDB Images (3)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Holding pen
B 08 May, 2017 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2