PDB Information

PDB5L6Y
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2.
Popovic, B., Breed, J., Rees, D.G., Gardener, M.J., Vinall, L.M., Kemp, B., Spooner, J., Keen, J., Minter, R., Uddin, F., Colice, G., Wilkinson, T., Vaughan, T., May, R.D.
J. Mol. Biol.
HeaderImmune System
Released2016-06-01
Resolution1.990
CATH Insert Date25 Dec, 2016

PDB Images (9)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
C 26 Dec, 2016 Chopped
H 26 Dec, 2016 Chopped
L 26 Dec, 2016 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
5l6yC00 30 Dec, 2016 1.20.1250.10 Assigned
5l6yH01 30 Dec, 2016 2.60.40.10 Assigned
5l6yH02 30 Dec, 2016 2.60.40.10 Assigned
5l6yL01 30 Dec, 2016 2.60.40.10 Assigned
5l6yL02 30 Dec, 2016 2.60.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P35225 IL13_HUMAN Homo sapiens Interleukin-13