PDB 5l58

PDB Links
Overview

PDB Information

PDB	5L58
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells. Jones, S., Ahmet, J., Ayton, K., Ball, M., Cockerill, M., Fairweather, E., Hamilton, N., Harper, P., Hitchin, J., Jordan, A., Levy, C., Lopez, R., McKenzie, E., Packer, M., Plant, D., Simpson, I., Simpson, P., Sinclair, I., Somervaille, T.C., Small, H., Spencer, G.J., Thomson, G., Tonge, M., Waddell, I., Walsh, J., Waszkowycz, B., Wigglesworth, M., Wiseman, D.H., Ogilvie, D. J.Med.Chem.
Header	Oxidoreductase
Released	2016-05-28
Resolution	3.040
CATH Insert Date	25 Dec, 2016

PDB Images (3)

Image of CATH 5l58

5l58

PDB 5l58

Image of CATH 5l58A

5l58A

PDB Chain 5l58A

Image of CATH 5l58A00

5l58A00

CATH Domain 5l58A00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	26 Dec, 2016	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5l58A00	30 Dec, 2016	3.40.718.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
O75874	IDHC_HUMAN	Homo sapiens	Isocitrate dehydrogenase [NADP] cytoplasmic