PDB 5l0k

PDB Links
Overview

PDB Information

PDB	5L0K
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Rattus norvegicus
Primary Citation	Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design. Jones, S.B., Pfeifer, L.A., Bleisch, T.J., Beauchamp, T.J., Durbin, J.D., Klimkowski, V.J., Hughes, N.E., Rito, C.J., Dao, Y., Gruber, J.M., Bui, H., Chambers, M.G., Chandrasekhar, S., Lin, C., McCann, D.J., Mudra, D.R., Oskins, J.L., Swearingen, C.A., Thirunavukkarasu, K., Norman, B.H. Acs Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-07-27
Resolution	2.730
CATH Insert Date	14 Aug, 2016

PDB Images (11)

Image of CATH 5l0k

5l0k

PDB 5l0k

Image of CATH 5l0kA

5l0kA

PDB Chain 5l0kA

Image of CATH 5l0kB

5l0kB

PDB Chain 5l0kB

Image of CATH 5l0kA01

5l0kA01

CATH Domain 5l0kA01

Image of CATH 5l0kA02

5l0kA02

CATH Domain 5l0kA02

Image of CATH 5l0kA03

5l0kA03

CATH Domain 5l0kA03

Image of CATH 5l0kA04

5l0kA04

CATH Domain 5l0kA04

Image of CATH 5l0kB01

5l0kB01

CATH Domain 5l0kB01

Image of CATH 5l0kB02

5l0kB02

CATH Domain 5l0kB02

Image of CATH 5l0kB03

5l0kB03

CATH Domain 5l0kB03

Image of CATH 5l0kB04

5l0kB04

CATH Domain 5l0kB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 Aug, 2016	Chopped
B	15 Aug, 2016	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5l0kA01	01 Sep, 2016		Holding pen
5l0kA02	01 Sep, 2016	4.10.410.20	Assigned
5l0kA03	01 Sep, 2016	3.40.720.10	Assigned
5l0kA04	01 Sep, 2016	3.40.570.10	Assigned
5l0kB01	01 Sep, 2016		Holding pen
5l0kB02	01 Sep, 2016	4.10.410.20	Assigned
5l0kB03	01 Sep, 2016	3.40.720.10	Assigned
5l0kB04	01 Sep, 2016	3.40.570.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q64610	ENPP2_RAT	Rattus norvegicus	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Q64610	ENPP2_RAT	Rattus norvegicus	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2