PDB 5l0e

PDB Links
Overview

PDB Information

PDB	5L0E
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Rattus norvegicus
Primary Citation	Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design. Jones, S.B., Pfeifer, L.A., Bleisch, T.J., Beauchamp, T.J., Durbin, J.D., Klimkowski, V.J., Hughes, N.E., Rito, C.J., Dao, Y., Gruber, J.M., Bui, H., Chambers, M.G., Chandrasekhar, S., Lin, C., McCann, D.J., Mudra, D.R., Oskins, J.L., Swearingen, C.A., Thirunavukkarasu, K., Norman, B.H. Acs Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-07-27
Resolution	3.060
CATH Insert Date	14 Aug, 2016

PDB Images (11)

Image of CATH 5l0e

5l0e

PDB 5l0e

Image of CATH 5l0eA

5l0eA

PDB Chain 5l0eA

Image of CATH 5l0eB

5l0eB

PDB Chain 5l0eB

Image of CATH 5l0eA01

5l0eA01

CATH Domain 5l0eA01

Image of CATH 5l0eA02

5l0eA02

CATH Domain 5l0eA02

Image of CATH 5l0eA03

5l0eA03

CATH Domain 5l0eA03

Image of CATH 5l0eA04

5l0eA04

CATH Domain 5l0eA04

Image of CATH 5l0eB01

5l0eB01

CATH Domain 5l0eB01

Image of CATH 5l0eB02

5l0eB02

CATH Domain 5l0eB02

Image of CATH 5l0eB03

5l0eB03

CATH Domain 5l0eB03

Image of CATH 5l0eB04

5l0eB04

CATH Domain 5l0eB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 Aug, 2016	Chopped
B	15 Aug, 2016	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5l0eA01	01 Sep, 2016		Holding pen
5l0eA02	01 Sep, 2016	4.10.410.20	Assigned
5l0eA03	01 Sep, 2016	3.40.720.10	Assigned
5l0eA04	01 Sep, 2016	3.40.570.10	Assigned
5l0eB01	01 Sep, 2016		Holding pen
5l0eB02	01 Sep, 2016	4.10.410.20	Assigned
5l0eB03	01 Sep, 2016	3.40.720.10	Assigned
5l0eB04	01 Sep, 2016	3.40.570.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q64610	ENPP2_RAT	Rattus norvegicus	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Q64610	ENPP2_RAT	Rattus norvegicus	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2