PDB 5kya

PDB Links
Overview

PDB Information

PDB	5KYA
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core. Tice, C.M., Noto, P.B., Fan, K.Y., Zhao, W., Lotesta, S.D., Dong, C., Marcus, A.P., Zheng, Y.J., Chen, G., Wu, Z., Van Orden, R., Zhou, J., Bukhtiyarov, Y., Zhao, Y., Lipinski, K., Howard, L., Guo, J., Kandpal, G., Meng, S., Hardy, A., Krosky, P., Gregg, R.E., Leftheris, K., McKeever, B.M., Singh, S.B., Lala, D., McGeehan, G.M., Zhuang, L., Claremon, D.A. Bioorg.Med.Chem.Lett.
Header	Dna Binding Protein
Released	2016-07-21
Resolution	2.600
CATH Insert Date	09 Oct, 2016

PDB Images (9)

Image of CATH 5kya

5kya

PDB 5kya

Image of CATH 5kyaA

5kyaA

PDB Chain 5kyaA

Image of CATH 5kyaB

5kyaB

PDB Chain 5kyaB

Image of CATH 5kyaE

5kyaE

PDB Chain 5kyaE

Image of CATH 5kyaF

5kyaF

PDB Chain 5kyaF

Image of CATH 5kyaA00

5kyaA00

CATH Domain 5kyaA00

Image of CATH 5kyaB00

5kyaB00

CATH Domain 5kyaB00

Image of CATH 5kyaE00

5kyaE00

CATH Domain 5kyaE00

Image of CATH 5kyaF00

5kyaF00

CATH Domain 5kyaF00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	10 Oct, 2016	Chopped
B	10 Oct, 2016	Chopped
E	10 Oct, 2016	Chopped
F	10 Oct, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5kyaA00	30 Nov, 2016	1.10.565.10	Assigned
5kyaB00	03 Jul, 2018	1.10.565.10	Assigned
5kyaE00	30 Nov, 2016	1.10.565.10	Assigned
5kyaF00	03 Jul, 2018	1.10.565.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28702	RXRB_HUMAN	Homo sapiens	Retinoic acid receptor RXR-beta
P55055	NR1H2_HUMAN	Homo sapiens	Oxysterols receptor LXR-beta
P28702	RXRB_HUMAN	Homo sapiens	Retinoic acid receptor RXR-beta
P55055	NR1H2_HUMAN	Homo sapiens	Oxysterols receptor LXR-beta