PDB 5kr8

PDB Information

PDB5KR8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine beta-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors.
Wu, Y.J., Guernon, J., Shi, J., Marcin, L., Higgins, M., Rajamani, R., Muckelbauer, J., Lewis, H., Chang, C., Camac, D., Toyn, J.H., Ahlijanian, M.K., Albright, C.F., Macor, J.E., Thompson, L.A.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2016-07-07
Resolution2.120
CATH Insert Date16 Oct, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5kr8A01 22 Oct, 2016 2.40.70.10 Assigned
5kr8A02 22 Oct, 2016 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1