PDB 5kos

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PDB Links
Overview

PDB Information

PDB	5KOS
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Homo sapiens
Primary Citation	Discovery of TAK-272: A Novel, Potent, and Orally Active Renin Inhibitor. Imaeda, Y., Tokuhara, H., Fukase, Y., Kanagawa, R., Kajimoto, Y., Kusumoto, K., Kondo, M., Snell, G., Behnke, C.A., Kuroita, T. Acs Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2016-07-01
Resolution	2.410
CATH Insert Date	27 Nov, 2016

PDB Images (7)

Image of CATH 5kos

5kos

PDB 5kos

Image of CATH 5kosA

5kosA

PDB Chain 5kosA

Image of CATH 5kosB

5kosB

PDB Chain 5kosB

Image of CATH 5kosA01

5kosA01

CATH Domain 5kosA01

Image of CATH 5kosA02

5kosA02

CATH Domain 5kosA02

Image of CATH 5kosB01

5kosB01

CATH Domain 5kosB01

Image of CATH 5kosB02

5kosB02

CATH Domain 5kosB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Nov, 2016	Chopped
B	28 Nov, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5kosA01	01 Dec, 2016	2.40.70.10	Assigned
5kosA02	01 Dec, 2016	2.40.70.10	Assigned
5kosB01	01 Dec, 2016	2.40.70.10	Assigned
5kosB02	01 Dec, 2016	2.40.70.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P00797	RENI_HUMAN	Homo sapiens	Renin
P00797	RENI_HUMAN	Homo sapiens	Renin