PDB Information

PDB5K4Z
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium thermoresistibile
Primary Citation
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
Park, Y., Pacitto, A., Bayliss, T., Cleghorn, L.A., Wang, Z., Hartman, T., Arora, K., Ioerger, T.R., Sacchettini, J., Rizzi, M., Donini, S., Blundell, T.L., Ascher, D.B., Rhee, K., Breda, A., Zhou, N., Dartois, V., Jonnala, S.R., Via, L.E., Mizrahi, V., Epemolu, O., Stojanovski, L., Simeons, F., Osuna-Cabello, M., Ellis, L., MacKenzie, C.J., Smith, A.R., Davis, S.H., Murugesan, D., Buchanan, K.I., Turner, P.A., Huggett, M., Zuccotto, F., Rebollo-Lopez, M.J., Lafuente-Monasterio, M.J., Sanz, O., Diaz, G.S., Lelievre, J., Ballell, L., Selenski, C., Axtman, M., Ghidelli-Disse, S., Pflaumer, H., Bosche, M., Drewes, G., Freiberg, G.M., Kurnick, M.D., Srikumaran, M., Kempf, D.J., Green, S.R., Ray, P.C., Read, K., Wyatt, P., Barry, C.E., Boshoff, H.I.
ACS Infect Dis
HeaderOxidoreductase
Released2016-05-22
Resolution1.640
CATH Insert Date20 Nov, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Nov, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5k4zA00 30 Nov, 2016 3.20.20.70 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
G7CNL4 G7CNL4_MYCT3 Mycolicibacterium thermoresistibile ATCC 19527 Inosine-5'-monophosphate dehydrogenase