PDB 5k1i

PDB Information

PDB5K1I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Biphenyl Pyridazinone Derivatives as Inhaled PDE4 Inhibitors: Structural Biology and Structure-Activity Relationships.
Gracia, J., Buil, M.A., Castro, J., Eichhorn, P., Ferrer, M., Gavalda, A., Hernandez, B., Segarra, V., Lehner, M.D., Moreno, I., Pages, L., Roberts, R.S., Serrat, J., Sevilla, S., Taltavull, J., Andres, M., Cabedo, J., Vilella, D., Calama, E., Carcasona, C., Miralpeix, M.
J. Med. Chem.
HeaderHydrolase
Released2016-05-18
Resolution2.610
CATH Insert Date25 Dec, 2016

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 26 Dec, 2016 Chopped
B 26 Dec, 2016 Chopped
C 26 Dec, 2016 Chopped
D 26 Dec, 2016 Chopped
E 26 Dec, 2016 Chopped
F 26 Dec, 2016 Chopped
G 26 Dec, 2016 Chopped
H 26 Dec, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5k1iA00 25 May, 2017 1.10.1300.10 Assigned
5k1iB00 25 May, 2017 1.10.1300.10 Assigned
5k1iC00 25 May, 2017 1.10.1300.10 Assigned
5k1iD00 25 May, 2017 1.10.1300.10 Assigned
5k1iE00 25 May, 2017 1.10.1300.10 Assigned
5k1iF00 25 May, 2017 1.10.1300.10 Assigned
5k1iG00 25 May, 2017 1.10.1300.10 Assigned
5k1iH00 25 May, 2017 1.10.1300.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Q08499 PDE4D_HUMAN Homo sapiens cAMP-specific 3',5'-cyclic phosphodiesterase 4D