PDB 5k09

PDB Information

PDB5K09
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceRattus norvegicus
Primary Citation
Design of Potent and Druglike Nonphenolic Inhibitors for Catechol O-Methyltransferase Derived from a Fragment Screening Approach Targeting the S-Adenosyl-l-methionine Pocket.
Lerner, C., Jakob-Roetne, R., Buettelmann, B., Ehler, A., Rudolph, M., Rodriguez Sarmiento, R.M.
J. Med. Chem.
HeaderTransferase
Released2016-05-17
Resolution2.700
CATH Insert Date02 Oct, 2016

PDB Images (49)

PDB Prints

PDB Chains (24)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped
C 03 Oct, 2016 Chopped
D 03 Oct, 2016 Chopped
E 03 Oct, 2016 Chopped
F 03 Oct, 2016 Chopped
G 03 Oct, 2016 Chopped
H 03 Oct, 2016 Chopped
I 03 Oct, 2016 Chopped
J 03 Oct, 2016 Chopped
K 03 Oct, 2016 Chopped
L 03 Oct, 2016 Chopped
M 03 Oct, 2016 Chopped
N 03 Oct, 2016 Chopped
O 03 Oct, 2016 Chopped
P 03 Oct, 2016 Chopped
Q 03 Oct, 2016 Chopped
R 03 Oct, 2016 Chopped
S 03 Oct, 2016 Chopped
T 03 Oct, 2016 Chopped
U 03 Oct, 2016 Chopped
V 03 Oct, 2016 Chopped
W 03 Oct, 2016 Chopped
X 03 Oct, 2016 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
5k09A00 20 Oct, 2016 3.40.50.150 Assigned
5k09B00 19 Oct, 2016 3.40.50.150 Assigned
5k09C00 20 Oct, 2016 3.40.50.150 Assigned
5k09D00 20 Oct, 2016 3.40.50.150 Assigned
5k09E00 19 Oct, 2016 3.40.50.150 Assigned
5k09F00 20 Oct, 2016 3.40.50.150 Assigned
5k09G00 20 Oct, 2016 3.40.50.150 Assigned
5k09H00 20 Oct, 2016 3.40.50.150 Assigned
5k09I00 20 Oct, 2016 3.40.50.150 Assigned
5k09J00 20 Oct, 2016 3.40.50.150 Assigned
5k09K00 20 Oct, 2016 3.40.50.150 Assigned
5k09L00 19 Oct, 2016 3.40.50.150 Assigned
5k09M00 19 Oct, 2016 3.40.50.150 Assigned
5k09N00 19 Oct, 2016 3.40.50.150 Assigned
5k09O00 20 Oct, 2016 3.40.50.150 Assigned
5k09P00 20 Oct, 2016 3.40.50.150 Assigned
5k09Q00 20 Oct, 2016 3.40.50.150 Assigned
5k09R00 20 Oct, 2016 3.40.50.150 Assigned
5k09S00 20 Oct, 2016 3.40.50.150 Assigned
5k09T00 20 Oct, 2016 3.40.50.150 Assigned
5k09U00 20 Oct, 2016 3.40.50.150 Assigned
5k09V00 20 Oct, 2016 3.40.50.150 Assigned
5k09W00 20 Oct, 2016 3.40.50.150 Assigned
5k09X00 20 Oct, 2016 3.40.50.150 Assigned

UniProtKB Entries (24)

Accession Gene ID Taxon Description
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase
P22734 COMT_RAT Rattus norvegicus Catechol O-methyltransferase