PDB 5jt2

PDB Information

PDB5JT2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation.
Grasso, M., Estrada, M.A., Ventocilla, C., Samanta, M., Maksimoska, J., Villanueva, J., Winkler, J.D., Marmorstein, R.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2016-05-09
Resolution2.700
CATH Insert Date02 Oct, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped
C 03 Oct, 2016 Chopped
D 03 Oct, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5jt2A01 07 Oct, 2016 3.30.200.20 Assigned
5jt2A02 07 Oct, 2016 1.10.510.10 Assigned
5jt2B01 07 Oct, 2016 3.30.200.20 Assigned
5jt2B02 07 Oct, 2016 1.10.510.10 Assigned
5jt2C01 07 Oct, 2016 3.30.200.20 Assigned
5jt2C02 07 Oct, 2016 1.10.510.10 Assigned
5jt2D01 07 Oct, 2016 3.30.200.20 Assigned
5jt2D02 07 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf