PDB 5jsm

PDB Information

PDB5JSM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation.
Grasso, M., Estrada, M.A., Ventocilla, C., Samanta, M., Maksimoska, J., Villanueva, J., Winkler, J.D., Marmorstein, R.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2016-05-08
Resolution2.190
CATH Insert Date02 Oct, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped
C 03 Oct, 2016 Chopped
D 03 Oct, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5jsmA01 07 Oct, 2016 3.30.200.20 Assigned
5jsmA02 07 Oct, 2016 1.10.510.10 Assigned
5jsmB01 07 Oct, 2016 3.30.200.20 Assigned
5jsmB02 07 Oct, 2016 1.10.510.10 Assigned
5jsmC01 07 Oct, 2016 3.30.200.20 Assigned
5jsmC02 07 Oct, 2016 1.10.510.10 Assigned
5jsmD01 07 Oct, 2016 3.30.200.20 Assigned
5jsmD02 07 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf