PDB 5izq

PDB	5IZQ
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Homo sapiens
Primary Citation	Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis. Golani, L.K., Wallace-Povirk, A., Deis, S.M., Wong, J., Ke, J., Gu, X., Raghavan, S., Wilson, M.R., Li, X., Polin, L., de Waal, P.W., White, K., Kushner, J., O'Connor, C., Hou, Z., Xu, H.E., Melcher, K., Dann, C.E., Matherly, L.H., Gangjee, A. J.Med.Chem.
Header	Signaling Protein
Released	2016-03-25
Resolution	3.600
CATH Insert Date	14 Aug, 2016

PDB 5izq

PDB Chain 5izqA

PDB Chain 5izqB

PDB Chain 5izqC

PDB Chain 5izqD

PDB Chain 5izqE

PDB Chain 5izqF

PDB Chain 5izqG

PDB Chain 5izqH

CATH Domain 5izqA00

CATH Domain 5izqB00

CATH Domain 5izqC00

CATH Domain 5izqD00

CATH Domain 5izqE00

CATH Domain 5izqF00

CATH Domain 5izqG00

CATH Domain 5izqH00

Domain ID	Date inserted into CATH	CATH Status
5izqA00	01 Sep, 2016	Holding pen
5izqB00	01 Sep, 2016	Holding pen
5izqC00	01 Sep, 2016	Holding pen
5izqD00	01 Sep, 2016	Holding pen
5izqE00	01 Sep, 2016	Holding pen
5izqF00	01 Sep, 2016	Holding pen
5izqG00	01 Sep, 2016	Holding pen
5izqH00	01 Sep, 2016	Holding pen

Accession	Gene ID	Taxon	Description