PDB 5ixs

PDB Information

PDB5IXS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice.
Purkey, H.E., Robarge, K., Chen, J., Chen, Z., Corson, L.B., Ding, C.Z., DiPasquale, A.G., Dragovich, P.S., Eigenbrot, C., Evangelista, M., Fauber, B.P., Gao, Z., Ge, H., Hitz, A., Ho, Q., Labadie, S.S., Lai, K.W., Liu, W., Liu, Y., Li, C., Ma, S., Malek, S., O'Brien, T., Pang, J., Peterson, D., Salphati, L., Sideris, S., Ultsch, M., Wei, B., Yen, I., Yue, Q., Zhang, H., Zhou, A.
Acs Med.Chem.Lett.
HeaderOxireductase/Oxireductase Inhibitor
Released2016-03-23
Resolution2.050
CATH Insert Date02 Oct, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped
C 03 Oct, 2016 Chopped
D 03 Oct, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5ixsA01 06 Oct, 2016 3.40.50.720 Assigned
5ixsA02 06 Oct, 2016 3.90.110.10 Assigned
5ixsB01 07 Oct, 2016 3.40.50.720 Assigned
5ixsB02 07 Oct, 2016 3.90.110.10 Assigned
5ixsC01 07 Oct, 2016 3.40.50.720 Assigned
5ixsC02 07 Oct, 2016 3.90.110.10 Assigned
5ixsD01 07 Oct, 2016 3.40.50.720 Assigned
5ixsD02 07 Oct, 2016 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
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