PDB 5iu2

PDB Links
Overview

PDB Information

PDB	5IU2
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Discovery of Imidazoquinolines as a Novel Class of Potent, Selective, and in Vivo Efficacious Cancer Osaka Thyroid (COT) Kinase Inhibitors. Glatthar, R., Stojanovic, A., Troxler, T., Mattes, H., Mobitz, H., Beerli, R., Blanz, J., Gassmann, E., Druckes, P., Fendrich, G., Gutmann, S., Martiny-Baron, G., Spence, F., Hornfeld, J., Peel, J.E., Sparrer, H. J.Med.Chem.
Header	Transferase
Released	2016-03-17
Resolution	2.700
CATH Insert Date	09 Oct, 2016

PDB Images (7)

Image of CATH 5iu2

5iu2

PDB 5iu2

Image of CATH 5iu2A

5iu2A

PDB Chain 5iu2A

Image of CATH 5iu2B

5iu2B

PDB Chain 5iu2B

Image of CATH 5iu2A01

5iu2A01

CATH Domain 5iu2A01

Image of CATH 5iu2A02

5iu2A02

CATH Domain 5iu2A02

Image of CATH 5iu2B01

5iu2B01

CATH Domain 5iu2B01

Image of CATH 5iu2B02

5iu2B02

CATH Domain 5iu2B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	10 Oct, 2016	Chopped
B	10 Oct, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5iu2A01	14 Oct, 2016	3.30.200.20	Assigned
5iu2A02	14 Oct, 2016	1.10.510.10	Assigned
5iu2B01	13 Oct, 2016	3.30.200.20	Assigned
5iu2B02	13 Oct, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P41279	M3K8_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase 8
P41279	M3K8_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase 8