PDB 5isp

PDB Information

PDB5ISP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceStaphylococcus aureus
Primary Citation
Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations.
Reeve, S.M., Scocchera, E., Ferreira, J.J., G-Dayanandan, N., Keshipeddy, S., Wright, D.L., Anderson, A.C.
J. Med. Chem.
HeaderOxidoreductase
Released2016-03-15
Resolution1.840
CATH Insert Date14 Nov, 2017

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
X 14 Nov, 2017 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5ispX00 10 Dec, 2017 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P0A017 DYR_STAAU Staphylococcus aureus Dihydrofolate reductase
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