PDB 5ime

PDB Links
Overview

PDB Information

PDB	5IME
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window. Rudolph, J., Murray, L.J., Ndubaku, C.O., O'Brien, T., Blackwood, E., Wang, W., Aliagas, I., Gazzard, L., Crawford, J.J., Drobnick, J., Lee, W., Zhao, X., Hoeflich, K.P., Favor, D.A., Dong, P., Zhang, H., Heise, C.E., Oh, A., Ong, C.C., La, H., Chakravarty, P., Chan, C., Jakubiak, D., Epler, J., Ramaswamy, S., Vega, R., Cain, G., Diaz, D., Zhong, Y. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2016-03-06
Resolution	2.220
CATH Insert Date	05 Jun, 2016

PDB Images (7)

Image of CATH 5ime

5ime

PDB 5ime

Image of CATH 5imeA

5imeA

PDB Chain 5imeA

Image of CATH 5imeB

5imeB

PDB Chain 5imeB

Image of CATH 5imeA01

5imeA01

CATH Domain 5imeA01

Image of CATH 5imeA02

5imeA02

CATH Domain 5imeA02

Image of CATH 5imeB01

5imeB01

CATH Domain 5imeB01

Image of CATH 5imeB02

5imeB02

CATH Domain 5imeB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	06 Jun, 2016	Chopped
B	06 Jun, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5imeA01	18 Jul, 2016	3.30.200.20	Assigned
5imeA02	18 Jul, 2016	1.10.510.10	Assigned
5imeB01	18 Jul, 2016	3.30.200.20	Assigned
5imeB02	18 Jul, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q13153	PAK1_HUMAN	Homo sapiens	Serine/threonine-protein kinase PAK 1
Q13153	PAK1_HUMAN	Homo sapiens	Serine/threonine-protein kinase PAK 1