PDB 5iis

PDB Information

PDB5IIS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold.
Nishiguchi, G.A., Burger, M.T., Han, W., Lan, J., Atallah, G., Tamez, V., Lindvall, M., Bellamacina, C., Garcia, P., Feucht, P., Zavorotinskaya, T., Dai, Y., Wong, K.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2016-03-01
Resolution2.100
CATH Insert Date17 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5iisA01 15 May, 2016 3.30.200.20 Assigned
5iisA02 15 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1