PDB 5ibk

PDB Information

PDB5IBK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1-F-box interface.
Gorelik, M., Orlicky, S., Sartori, M.A., Tang, X., Marcon, E., Kurinov, I., Greenblatt, J.F., Tyers, M., Moffat, J., Sicheri, F., Sidhu, S.S.
Proc.Natl.Acad.Sci.USA
HeaderProtein Binding
Released2016-02-22
Resolution2.500
CATH Insert Date10 Apr, 2016

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped
E 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5ibkA00 15 May, 2016 3.30.710.10 Assigned
5ibkB00 15 May, 2016 1.20.1280.50 Assigned
5ibkC00 15 May, 2016 Holding pen
5ibkD00 15 May, 2016 3.30.710.10 Assigned
5ibkE00 15 May, 2016 1.20.1280.50 Assigned
5ibkF00 15 May, 2016 Holding pen

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P63208 SKP1_HUMAN Homo sapiens S-phase kinase-associated protein 1
Q969H0 FBXW7_HUMAN Homo sapiens F-box/WD repeat-containing protein 7
P63208 SKP1_HUMAN Homo sapiens S-phase kinase-associated protein 1
P0CG47 UBB_HUMAN Homo sapiens Polyubiquitin-B
Q969H0 FBXW7_HUMAN Homo sapiens F-box/WD repeat-containing protein 7
P0CG47 UBB_HUMAN Homo sapiens Polyubiquitin-B