PDB 5i4v

PDB Links
Overview

PDB Information

PDB	5I4V
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) beta Agonist. Zheng, Y., Zhuang, L., Fan, K.Y., Tice, C.M., Zhao, W., Dong, C., Lotesta, S.D., Leftheris, K., Lindblom, P.R., Liu, Z., Shimada, J., Noto, P.B., Meng, S., Hardy, A., Howard, L., Krosky, P., Guo, J., Lipinski, K., Kandpal, G., Bukhtiyarov, Y., Zhao, Y., Lala, D., Van Orden, R., Zhou, J., Chen, G., Wu, Z., McKeever, B.M., McGeehan, G.M., Gregg, R.E., Claremon, D.A., Singh, S.B. J.Med.Chem.
Header	Dna Binding Protein
Released	2016-02-12
Resolution	2.610
CATH Insert Date	10 Jul, 2016

PDB Images (9)

Image of CATH 5i4v

5i4v

PDB 5i4v

Image of CATH 5i4vA

5i4vA

PDB Chain 5i4vA

Image of CATH 5i4vB

5i4vB

PDB Chain 5i4vB

Image of CATH 5i4vE

5i4vE

PDB Chain 5i4vE

Image of CATH 5i4vF

5i4vF

PDB Chain 5i4vF

Image of CATH 5i4vA00

5i4vA00

CATH Domain 5i4vA00

Image of CATH 5i4vB00

5i4vB00

CATH Domain 5i4vB00

Image of CATH 5i4vE00

5i4vE00

CATH Domain 5i4vE00

Image of CATH 5i4vF00

5i4vF00

CATH Domain 5i4vF00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	11 Jul, 2016	Chopped
B	11 Jul, 2016	Chopped
E	11 Jul, 2016	Chopped
F	11 Jul, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5i4vA00	30 Nov, 2016	1.10.565.10	Assigned
5i4vB00	03 Jul, 2018	1.10.565.10	Assigned
5i4vE00	30 Nov, 2016	1.10.565.10	Assigned
5i4vF00	03 Jul, 2018	1.10.565.10	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P55055	NR1H2_HUMAN	Homo sapiens	Oxysterols receptor LXR-beta
Q15596	NCOA2_HUMAN	Homo sapiens	Nuclear receptor coactivator 2
P55055	NR1H2_HUMAN	Homo sapiens	Oxysterols receptor LXR-beta
Q15596	NCOA2_HUMAN	Homo sapiens	Nuclear receptor coactivator 2
Q15596	NCOA2_HUMAN	Homo sapiens	Nuclear receptor coactivator 2
P28702	RXRB_HUMAN	Homo sapiens	Retinoic acid receptor RXR-beta
Q15596	NCOA2_HUMAN	Homo sapiens	Nuclear receptor coactivator 2
P28702	RXRB_HUMAN	Homo sapiens	Retinoic acid receptor RXR-beta