PDB 5hzn
PDB Information
| PDB | 5HZN |
| Method | X-RAY DIFFRACTION |
| Host Organism | unidentified baculovirus |
| Gene Source | Homo sapiens |
| Primary Citation | Identification of a 5-[3-phenyl-(2-cyclic-ether)-methylether]-4-aminopyrrolo[2,3-d]pyrimidine series of IGF-1R inhibitors.
Bioorg.Med.Chem.Lett.
|
| Header | Transferase |
| Released | 2016-02-02 |
| Resolution | 2.200 |
| CATH Insert Date | 17 Apr, 2016 |
PDB Images (25)
5hzn
PDB 5hzn
5hznA
PDB Chain 5hznA
5hznB
PDB Chain 5hznB
5hznC
PDB Chain 5hznC
5hznD
PDB Chain 5hznD
5hznE
PDB Chain 5hznE
5hznF
PDB Chain 5hznF
5hznG
PDB Chain 5hznG
5hznH
PDB Chain 5hznH
5hznA01
CATH Domain 5hznA01
5hznA02
CATH Domain 5hznA02
5hznB01
CATH Domain 5hznB01
5hznB02
CATH Domain 5hznB02
5hznC01
CATH Domain 5hznC01
5hznC02
CATH Domain 5hznC02
5hznD01
CATH Domain 5hznD01
5hznD02
CATH Domain 5hznD02
5hznE01
CATH Domain 5hznE01
5hznE02
CATH Domain 5hznE02
5hznF01
CATH Domain 5hznF01
5hznF02
CATH Domain 5hznF02
5hznG01
CATH Domain 5hznG01
5hznG02
CATH Domain 5hznG02
5hznH01
CATH Domain 5hznH01
5hznH02
CATH Domain 5hznH02
PDB Prints
PDB Chains (8)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 18 Apr, 2016 | Chopped |
| B | 18 Apr, 2016 | Chopped |
| C | 18 Apr, 2016 | Chopped |
| D | 18 Apr, 2016 | Chopped |
| E | 18 Apr, 2016 | Chopped |
| F | 18 Apr, 2016 | Chopped |
| G | 18 Apr, 2016 | Chopped |
| H | 18 Apr, 2016 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5hznA01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznA02 | 15 May, 2016 | 1.10.510.10 | Assigned |
| 5hznB01 | 14 May, 2016 | 3.30.200.20 | Assigned |
| 5hznB02 | 14 May, 2016 | 1.10.510.10 | Assigned |
| 5hznC01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznC02 | 15 May, 2016 | 1.10.510.10 | Assigned |
| 5hznD01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznD02 | 15 May, 2016 | 1.10.510.10 | Assigned |
| 5hznE01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznE02 | 15 May, 2016 | 1.10.510.10 | Assigned |
| 5hznF01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznF02 | 15 May, 2016 | 1.10.510.10 | Assigned |
| 5hznG01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznG02 | 15 May, 2016 | 1.10.510.10 | Assigned |
| 5hznH01 | 15 May, 2016 | 3.30.200.20 | Assigned |
| 5hznH02 | 15 May, 2016 | 1.10.510.10 | Assigned |
UniProtKB Entries (8)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
| P08069 | IGF1R_HUMAN | Homo sapiens | Insulin-like growth factor 1 receptor |
