PDB 5hx8

PDB Links
Overview

PDB Information

PDB	5HX8
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors. Simov, V., Deshmukh, S.V., Dinsmore, C.J., Elwood, F., Fernandez, R.B., Garcia, Y., Gibeau, C., Gunaydin, H., Jung, J., Katz, J.D., Kraybill, B., Lapointe, B., Patel, S.B., Siu, T., Su, H., Young, J.R. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2016-01-29
Resolution	2.200
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 5hx8

5hx8

PDB 5hx8

Image of CATH 5hx8A

5hx8A

PDB Chain 5hx8A

Image of CATH 5hx8B

5hx8B

PDB Chain 5hx8B

Image of CATH 5hx8A01

5hx8A01

CATH Domain 5hx8A01

Image of CATH 5hx8A02

5hx8A02

CATH Domain 5hx8A02

Image of CATH 5hx8B01

5hx8B01

CATH Domain 5hx8B01

Image of CATH 5hx8B02

5hx8B02

CATH Domain 5hx8B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5hx8A01	14 May, 2016	3.30.200.20	Assigned
5hx8A02	14 May, 2016	1.10.510.10	Assigned
5hx8B01	15 May, 2016	3.30.200.20	Assigned
5hx8B02	15 May, 2016	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P23458	JAK1_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK1
P23458	JAK1_HUMAN	Homo sapiens	Tyrosine-protein kinase JAK1