PDB 5hs3

PDB Information

PDB5HS3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Almqvist, H., Axelsson, H., Jafari, R., Chen, D., Mateus, A., Haraldsson, M., Larsson, A., Molina, D.M., Artursson, P., Lundback, T., Nordlund, P.
Nat Commun
HeaderTransferase/Transferase Inhibitor
Released2016-01-25
Resolution3.100
CATH Insert Date10 Apr, 2016

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped
E 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
5hs3A00 14 May, 2016 3.30.572.10 Assigned
5hs3B00 14 May, 2016 3.30.572.10 Assigned
5hs3C00 14 May, 2016 3.30.572.10 Assigned
5hs3D00 14 May, 2016 3.30.572.10 Assigned
5hs3E00 14 May, 2016 3.30.572.10 Assigned
5hs3F00 14 May, 2016 3.30.572.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
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