PDB Information

PDB5HOA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).
Ugolini, A., Kenigsberg, M., Rak, A., Vallee, F., Houtmann, J., Lowinski, M., Capdevila, C., Khider, J., Albert, E., Martinet, N., Nemecek, C., Grapinet, S., Bacque, E., Roesner, M., Delaisi, C., Calvet, L., Bonche, F., Semiond, D., Egile, C., Goulaouic, H., Schio, L.
J.Med.Chem.
HeaderTransferase
Released2016-01-19
Resolution2.140
CATH Insert Date04 Dec, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Dec, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5hoaA01 09 Dec, 2016 Sam cath gather
5hoaA02 09 Dec, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor