PDB 5hls

PDB Information

PDB5HLS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials.
Albrecht, B.K., Gehling, V.S., Hewitt, M.C., Vaswani, R.G., Cote, A., Leblanc, Y., Nasveschuk, C.G., Bellon, S., Bergeron, L., Campbell, R., Cantone, N., Cooper, M.R., Cummings, R.T., Jayaram, H., Joshi, S., Mertz, J.A., Neiss, A., Normant, E., O'Meara, M., Pardo, E., Poy, F., Sandy, P., Supko, J., Sims, R.J., Harmange, J.C., Taylor, A.M., Audia, J.E.
J.Med.Chem.
HeaderTranscription
Released2016-01-15
Resolution2.180
CATH Insert Date10 Apr, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5hlsA01 14 May, 2016 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4