PDB Information

PDB5HE1
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.
Waldschmidt, H.V., Homan, K.T., Cruz-Rodriguez, O., Cato, M.C., Waninger-Saroni, J., Larimore, K.M., Cannavo, A., Song, J., Cheung, J.Y., Kirchhoff, P.D., Koch, W.J., Tesmer, J.J., Larsen, S.D.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2016-01-05
Resolution3.150
CATH Insert Date29 May, 2016

PDB Images (11)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped
G 30 May, 2016 Chopped

CATH Domains (7)

Domain ID Date inserted into CATH Superfamily CATH Status
5he1A01 28 Feb, 2017 New
5he1A02 28 Feb, 2017 1.10.167.10 Assigned
5he1A03 28 Feb, 2017 3.30.200.20 Assigned
5he1A04 28 Feb, 2017 1.10.510.10 Assigned
5he1A05 28 Feb, 2017 2.30.29.30 Assigned
5he1B00 16 Jul, 2016 2.130.10.10 Assigned
5he1G00 16 Jul, 2016 4.10.260.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P25098 ARBK1_HUMAN Homo sapiens Beta-adrenergic receptor kinase 1
P59768 GBG2_HUMAN Homo sapiens Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
P62873 GBB1_HUMAN Homo sapiens Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1