PDB 5gwk
PDB Information
| PDB | 5GWK |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry
Nucleic Acids Res.
|
| Header | Isomerase/Dna/Isomerase Inhibitor |
| Released | 2016-09-12 |
| Resolution | 3.150 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Images (17)
5gwk
PDB 5gwk
5gwkA
PDB Chain 5gwkA
5gwkB
PDB Chain 5gwkB
5gwkC
PDB Chain 5gwkC
5gwkD
PDB Chain 5gwkD
5gwkE
PDB Chain 5gwkE
5gwkF
PDB Chain 5gwkF
5gwkA01
CATH Domain 5gwkA01
5gwkA02
CATH Domain 5gwkA02
5gwkA03
CATH Domain 5gwkA03
5gwkA04
CATH Domain 5gwkA04
5gwkA05
CATH Domain 5gwkA05
5gwkB01
CATH Domain 5gwkB01
5gwkB02
CATH Domain 5gwkB02
5gwkB03
CATH Domain 5gwkB03
5gwkB04
CATH Domain 5gwkB04
5gwkB05
CATH Domain 5gwkB05
PDB Prints
PDB Chains (6)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
| B | 14 Nov, 2017 | Chopped |
| C | 14 Nov, 2017 | Rejected |
| D | 14 Nov, 2017 | Rejected |
| E | 14 Nov, 2017 | Rejected |
| F | 14 Nov, 2017 | Rejected |
CATH Domains (10)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5gwkA01 | 10 Dec, 2017 | 3.40.50.670 | Assigned |
| 5gwkA02 | 10 Dec, 2017 | 3.30.1490.30 | Assigned |
| 5gwkA03 | 10 Dec, 2017 | 3.90.199.10 | Assigned |
| 5gwkA04 | 10 Dec, 2017 | 3.30.1360.40 | Assigned |
| 5gwkA05 | 10 Dec, 2017 | 1.10.268.10 | Assigned |
| 5gwkB01 | 10 Dec, 2017 | 3.40.50.670 | Assigned |
| 5gwkB02 | 10 Dec, 2017 | 3.30.1490.30 | Assigned |
| 5gwkB03 | 10 Dec, 2017 | 3.90.199.10 | Assigned |
| 5gwkB04 | 10 Dec, 2017 | 3.30.1360.40 | Assigned |
| 5gwkB05 | 10 Dec, 2017 | 1.10.268.10 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P11388 | TOP2A_HUMAN | Homo sapiens | DNA topoisomerase 2-alpha |
| P11388 | TOP2A_HUMAN | Homo sapiens | DNA topoisomerase 2-alpha |
