PDB 5gnk

PDB Information

PDB5GNK
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode.
Wang, A., Li, X., Wu, H., Zou, F., Yan, X.E., Chen, C., Hu, C., Yu, K., Wang, W., Zhao, P., Wu, J., Qi, Z., Wang, W., Wang, B., Wang, L., Ren, T., Zhang, S., Yun, C.H., Liu, J., Liu, Q.
J. Med. Chem.
HeaderTransferase
Released2016-07-21
Resolution1.800
CATH Insert Date07 May, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 May, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5gnkA01 12 May, 2017 3.30.200.20 Assigned
5gnkA02 12 May, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor