PDB 5gmp

PDB Information

PDB5GMP
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFR(L858R/T790M) mutant with improved pharmacokinetic properties.
Yu, L., Huang, M., Xu, T., Tong, L., Yan, X.E., Zhang, Z., Xu, Y., Yun, C., Xie, H., Ding, K., Lu, X.
Eur J Med Chem
HeaderTransferase
Released2016-07-14
Resolution2.800
CATH Insert Date14 Nov, 2017

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Nov, 2017 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5gmpA01 10 Dec, 2017 3.30.200.20 Assigned
5gmpA02 10 Dec, 2017 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
CATH-Gene3D is a Global Biodata Core Resource Learn more...