PDB 5gmp
PDB Information
| PDB | 5GMP |
| Method | X-RAY DIFFRACTION |
| Host Organism | Spodoptera frugiperda |
| Gene Source | Homo sapiens |
| Primary Citation | A structure-guided optimization of pyrido[2,3-d]pyrimidin-7-ones as selective inhibitors of EGFR(L858R/T790M) mutant with improved pharmacokinetic properties.
Eur J Med Chem
|
| Header | Transferase |
| Released | 2016-07-14 |
| Resolution | 2.800 |
| CATH Insert Date | 14 Nov, 2017 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 14 Nov, 2017 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 5gmpA01 | 10 Dec, 2017 | 3.30.200.20 | Assigned |
| 5gmpA02 | 10 Dec, 2017 | 1.10.510.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P00533 | EGFR_HUMAN | Homo sapiens | Epidermal growth factor receptor |