PDB 5ftq

PDB Information

PDB5FTQ
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Discovery of Entrectinib: A New 3-Aminoindazole as a Potent Anaplastic Lymphoma Kinase (Alk), C-Ros Oncogene 1 Kinase (Ros1), and Pan-Tropomyosin Receptor Kinases (Pan-Trks) Inhibitor.
Menichincheri, M., Ardini, E., Magnaghi, P., Avanzi, N., Banfi, P., Bossi, R.T., Buffa, L., Canevari, G., Ceriani, L., Colombo, M., Corti, L., Donati, D., Fasolini, M., Felder, E.R., Fiorelli, C., Fiorentini, F., Galvani, A., Isacchi, A., Borgia, A.L., Marchionni, C., Nesi, M., Orrenius, C., Panzeri, A., Pesenti, E., Rusconi, L., Saccardo, B.M., Vanotti, E., Perrone, E., Orsini, P.
J.Med.Chem.
HeaderTransferase
Released2016-01-14
Resolution1.700
CATH Insert Date17 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5ftqA01 12 May, 2016 3.30.200.20 Assigned
5ftqA02 12 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor